The Chun-Li singer was asked by a fan if she was dating the Loose Yourself star Eminem, real name Marshall Bruce Mathers III, on the social media site.
And Nicki, 35, seemed to put rumours to bed, as she simply replied: “Yes”.
Fans began to go wild online after news got out of the pairing.
While another added: “This is Wild! Nicki Minaj says yes when a fan asked her if she’s dating Eminem.”
A third continued: “Apparently Nicki Minaj and Eminem are dating and I don’t know how I feel about [it]… I’m speechless right now.”
However, others were more sceptical about whether Nicki, real name Onika Tanya Maraj, was actually dating Eminem.
Another added: “I refuse to believe that Nicki Minaj and Eminem are f***ing… Oh hell no.”
A third chimed in: “Nicki Minaj is dating Eminem? We love a publicity stunt.”
Nicki has a string of famous rapper exes including Nas, Meek Mill, Lil Wayne and Drake.
He was also married to Kimberly Anne Scott between 1999-2001 and 2006.
Eminem is father to Alaina Marie Mathers, 25, Hailie Jade, 22, Whitney Scott Mather, 16.